Matthew Honea Matthew Honea AI-native CISO
CISO · Advisor · Writer

Security leadership for the AI-native enterprise.

Matthew Honea is the Chief Information Security Officer at Hippocratic AI. He has led security at hyper-growth startups, public companies, and the U.S. Department of State, and advises founders and venture firms on building security into AI-native companies.

39published articles and whitepapers
21keynotes, panels, and interviews
5advisory boards
3venture firms advised
session · matthewhonea.com ask anything about my work
you › who are you, and what do you work on?
honea I am Matthew Honea, an AI-native security leader. I am the CISO at Hippocratic AI, a healthcare AI company focused on patient care and safety. I advise Tailscale, CloudFence, Fable, Cygnvs, and the Silicon Valley Japan Platform, serve as a CxO Advisor at Greylock Partners and a Venture Advisor at Glilot Capital and YL Ventures, and have angel-invested in five security companies. My work spans enterprise security, AI safety, and cyber risk quantification across AI, healthcare, insurance, finance, media, and government. Pick a prompt below to keep going.
›
01 · Profile

Human Model Card

role, advisory, and focus
honea-2026 arch: security-leadership context: enterprise + AI status: available
Role
CISO, Hippocratic AI
Capital
Greylock Partners CxO Advisor · Glilot Capital Venture Advisor · YL Ventures Venture Advisor · angel investor, 5 security companies
Focus
Enterprise security, AI safety, cyber risk quantification
Sectors
AI, healthcare, insurance, finance, media, government
Outputs
39 published articles and whitepapers
Recognition
40 Under 40, Silicon Valley Business Journal
human voice

Security professional and industry speaker. My experience spans media, finance, insurance, and government, with emphasis on software products, data science, and enterprise security.

I work directly with customers, vendors, and partners to ensure success, and I write about quantifying individual and aggregated cyber risk for public and private organizations.

Silicon Valley Business Journal

In 2019, recognized as one of the most influential young people in Silicon Valley business and named to 40 Under 40.

02 · Writing

Writing & Publications

39 pieces · 2017 to 2026
published & cited by
SecurityWeek Dark Reading Help Net Security CISO Series Insurance Journal Risk & Insurance Reuters Lloyd's of London
full record
03 · Speaking

Interviews & Invited Talks

21 engagements · keynotes, panels, podcasts
2026.08 · webinar

Are You Ready for Your Next AI Incident?

With CYGNVS founder Arvind Parthasarathi: why cyber incident response falls short for AI failures, and how to build readiness across teams.

Watch online →
2026.01 · panel

SecurityWeek CISO Forum: 2026 Outlook

A CISO's playbook for a smarter, leaner security stack: where AI cuts operational load, where it adds hidden risk, and how to measure its return.

Watch online →
2025.10 · moderator

SVJP Benkyokai: Voice and Human-Centric AI

Moderated a conversation with Dr. Kinuko Masaki of VoiceBrain on voice analytics and real-time decisions in public safety.

More info →
2024.10 · fireside chat

Oktane 2024

Fireside chat at Caesars Forum in Las Vegas on identity, security, and where the technology is heading, with leaders from Okta and Openlane.

More info →
run · keynote

SWISH GIST 24

Practical security applications for attack surface management using digital twin technology.

More info →
run · session

Security Field Day

A sponsored session with specialists worldwide on finding and fixing network device vulnerabilities.

Watch online →
earlier runs
webinar
headlines
CISO SeriesCISO Series →
benkyokai
US Japan CouncilUS Japan Council →
panel
The Security SummitThe Security Summit →
podcast
Security ConversationsSecurity Conversations →
conference
Silicon Valley Japan ProjectSilicon Valley Japan Project →
panel
National Cybersecurity AllianceNational Cybersecurity Alliance →
lecture
talk
webcast
research
Casualty Actuarial SocietyCasualty Actuarial Society →
keynote
Guidewire ConnectionsGuidewire Connections →
04 · Contact

About & Connect

open to conversations
Matthew Honea

Security professional and industry speaker working where AI, healthcare, and the enterprise meet.

My experience spans media, finance, insurance, and government, with emphasis on software products, data science, and enterprise security. I work directly with customers, vendors, and partners to ensure success.

roleCISO, Hippocratic AI
advisoryTailscale · CloudFence · Fable · Cygnvs · SV Japan Platform
capitalGreylock · Glilot · YL Ventures · angel (5 cos.)
status● open to conversations

AI lives on the endpoint.
So does the future of security.